{"product_id":"glutathione-1500-mg","title":"Glutathione – 1500 mg","description":"\u003cdiv class=\"qvg-desc-rt\"\u003e\n\u003cstyle\u003e.qvg-desc-rt{font-family:'Neue Montreal',Helvetica,Arial,sans-serif;color:#6f7f84}.qvg-desc-rt p{margin:0 0 15px;font-size:15.5px;font-weight:300;line-height:1.7}.qvg-desc-rt strong{color:#233137;font-weight:500}.qvg-desc-rt em{color:#8a969b}.qvg-desc-rt sup{line-height:0}.qvg-desc-rt sup a{font-size:11px;font-weight:600;color:#758084;text-decoration:none;padding:0 1px}.qvg-desc-rt sup a:hover{color:#233137}\u003c\/style\u003e\n\u003cp\u003e\u003cstrong\u003eGlutathione\u003c\/strong\u003e is the tripeptide \u003cstrong\u003eγ-L-glutamyl-L-cysteinylglycine\u003c\/strong\u003e, the most abundant \u003cstrong\u003enon-protein thiol\u003c\/strong\u003e in mammalian cells, at millimolar concentration.\u003c\/p\u003e\n\u003cp\u003eIts \u003cstrong\u003eγ-linkage\u003c\/strong\u003e, on the glutamate side chain and not the α-carbon, resists most peptidases, and it is made by two cytosolic enzymes, not by ribosomes. In mammals, \u003cstrong\u003eeight glutathione peroxidases\u003c\/strong\u003e (GPx1 to GPx8) have been described\u003csup\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.bbagen.2012.11.020\" target=\"_blank\" rel=\"noopener\"\u003e[1]\u003c\/a\u003e\u003c\/sup\u003e.\u003c\/p\u003e\n\u003cp\u003eGlutathione is the cofactor these peroxidases use, along with the \u003cstrong\u003eS-transferases\u003c\/strong\u003e and glyoxalases, and the \u003cstrong\u003eGSH\/GSSG ratio\u003c\/strong\u003e is the standard redox index. Reversible \u003cstrong\u003eS-glutathionylation\u003c\/strong\u003e of protein cysteines is reported as a redox signal\u003csup\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/bs.vh.2022.09.002\" target=\"_blank\" rel=\"noopener\"\u003e[2]\u003c\/a\u003e\u003c\/sup\u003e.\u003c\/p\u003e\n\u003cp\u003eSupplied as a \u003cstrong\u003elyophilized powder\u003c\/strong\u003e for reconstitution. \u003cem\u003eFindings above come from preclinical (animal and cell-based) research on these molecules and are provided as scientific reference for laboratory research only.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Qovigen Peptides","offers":[{"title":"Default Title","offer_id":49587397886179,"sku":"GTT1500","price":70.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0777\/1029\/5267\/files\/qovigen-glutathione-1500mg.webp?v=1787559361","url":"https:\/\/qovigen.com\/products\/glutathione-1500-mg","provider":"Qovigen Peptides","version":"1.0","type":"link"}